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MME Calculator

Convert opioid doses to morphine milligram equivalents (MME) to compare potency and understand risk thresholds. Educational use only.

Calculate MME

Results

75
Total MME per day
Risk Level: INCREASED

Breakdown by Drug:

oxycodone
40 mg/day
60 MME
×1.5
morphine
15 mg/day
15 MME
×1
Important Warnings:
  • • Elevated overdose risk at ≥50 MME/day (CDC caution).
  • • Not a prescription tool. Clinical judgment required.
  • • Methadone and fentanyl conversions are approximate; specialist input recommended.

MME Risk Categories

Low Risk<50 MME/day

Standard monitoring recommended

  • • Regular follow-up visits
  • • Standard precautions
Increased Risk≥50 MME/day

CDC caution threshold

  • • Enhanced monitoring required
  • • Consider risk mitigation strategies
High Risk≥90 MME/day

Significant overdose risk

  • • Intensive monitoring required
  • • Consider dose reduction or rotation

How to Calculate MME

Conversion Formula

Basic Formula: MME = Daily Dose (mg) × Conversion Factor
Fentanyl Patch: MME = mcg/hr × 2.4
Methadone: Non-linear conversion (dose-dependent)

Calculation Steps:

  1. 1
    Select the opioid drug
    Choose from supported medications
  2. 2
    Enter dose and frequency
    Input daily dose in mg (or mcg/hr for patches)
  3. 3
    Apply conversion factor
    Multiply by drug-specific MME factor

Important Considerations

⚠️ Medical Disclaimer

This calculator provides estimates for educational purposes only. Not for prescribing decisions.

🧬 Individual Variations

MME conversions vary by individual factors

  • • Tolerance and metabolism
  • • Route of administration
  • • Chronic vs acute use
💊 Drug Interactions

Other medications affect opioid effects

  • • CNS depressants increase risk
  • • CYP enzyme interactions
  • • Drug-drug interactions
📊 Risk Assessment

Multiple factors determine overdose risk

  • • Age and comorbidities
  • • Substance use history
  • • Social support factors
⚕️ Safety Warnings

Critical safety considerations

  • • Not for prescribing decisions
  • • Educational use only
  • • Consult healthcare providers

Example Cases

Case 1: Post-Surgical Pain Management

Medications: Oxycodone 10mg q6h
Additional: Morphine 15mg daily
Duration: 3 days post-op
Total MME: 75 MME/day
Risk Level: Increased
Monitoring: Enhanced required

Use Case: Short-term post-surgical pain requiring close monitoring due to elevated MME levels.

Case 2: Chronic Pain Management

Medications: Methadone 20mg daily
Additional: Tramadol 50mg q8h
Duration: Long-term therapy
Total MME: 88 MME/day
Risk Level: High
Monitoring: Intensive required

Use Case: Chronic pain requiring specialist input and careful risk-benefit assessment.

Frequently Asked Questions

What is MME?
MME (Morphine Milligram Equivalent) converts different opioid doses into a morphine-equivalent amount to standardize potency for comparison and risk awareness.
Which drugs are supported?
Common opioids such as morphine, oxycodone, hydrocodone, hydromorphone, codeine, tramadol, tapentadol, methadone, and fentanyl patches.
Are these conversions exact?
No. Conversions are approximate and context-dependent (route, chronic vs acute use, tolerance). Methadone and fentanyl require extra caution.
Is this medical advice?
No. This tool is for educational purposes only and does not provide medical advice or prescribing recommendations.
What thresholds matter?
Guidelines often flag ≥50 MME/day for increased risk and ≥90 MME/day for high risk. Clinical judgment and local guidelines should prevail.

Related Calculators

MME Calculator - Opioid Dose to Morphine Equivalents